8 Best Eyelash Growth Serums That Our Testers Say Actually Work

Derms tell Glamour Latisse is technically the only real proven lash enhancer. “Bimatoprost, a prescription-strength prostaglandin found in Latisse, targets the hair follicles, effectively starting at the source of lash health—which is why it makes for the best lash serums,” says Melanie Palm, MD, a board-certified dermatologist. It does have its downside, though. Prescription-strength prostaglandins carry the risk of some side effects, like discoloration of the skin and iris. Plus, this key ingredient means those who are pregnant or breastfeeding shouldn’t use the beauty product.

More readily available OTC lash serums contain less potent ingredients like hyaluronic acid and panthenol (a.k.a. vitamin B5) or amino acids like arginine to boost keratin and improve overall hair health. While they do work, they take longer (a few months as opposed to a couple of weeks) to work their magic and may not yield as dramatic results, says Dr. Palm.

“As we age, our lashes undergo a decrease in density and fullness,” says Melanie Palm, MD, a board-certified dermatologist in San Diego. And “mascara, eye-makeup removers, glue from eyelash extensions, and eyelash curlers can cause damage,” says Diane Hilal-Campo, MD, a board-certified ophthalmologist in Oakland, New Jersey. But besides all that, brittle lashes and hair loss is actually quite common.